X-5 Plus

X-5 Plus

Hemoglobin Analyzer (HPLC)

The fully automated aranax X-5 Plus Hemoglobin Analyzer offers the fast throughput of HbA1c results in 130 seconds, with Hb variant detection, providing the outstanding solution for quick and reliable diabetic monitoring. No sample preparation and very little hands-on time by the operator is required for the X-5 Plus Analyzer.

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Gold Standard of Diabetes Diagnose

Glycosylated hemoglobin (HbA1c) is widely recognized as a Gold Standard to monitor diabetes, which can indicate the average plasma glucose concentration over 8–12 weeks.

HPLC Methodology

High-Pressure Liquid Chromatography (HPLC), to separate HbA1c, HbF, HbA2 directly with measuring the absorbance points continually to form chromatogram. Using normal distribution curve fitting auto-iterative algorithm to get precise HbA1c testing result, excluding interference of variant and unstable hemoglobin. Standard Analysis Mode will report HbA1a, HbA1b, HbF, La1c, HbA1c, HbA0 peak areas and ratio. And the result also includes IFCC, NGSP and ADAG value for diverse client needs.

The Elements of Hemoglobin
  • Hb (Hemoglobin)
    • HbA (Adult hemoglobin – 97%)
    • HbA2 (2.5%)
    • HbF (0.5%, fetal hemoglobin)
    • HbVariant (HbS, HbD, HbC, HbE, etc.)
  • HbA0 (94%) – Non-glycated Hb
  • HbA1 (6%) – Glycated Hb (HbA1a, HbA1b, HbA1c, HbA1e)
    • bA1c: Forms from the combination between HbA and glucose, 60–70% of total HbA1
HPLC Technology – Gold Standard Methodology
  • NGSP and IFCC Certified
  • HbA1c Results in 130 Seconds
Fully Automated – To Minimize Operation Hassles
  • Fully Automated Start-up, Maintenance and Shutdown
  • Primary Tube Sampling with Cap Piercing
  • Barcode Scanner for Sample Identification
Precise and Reliable – To Serve You Consistently
  • HbA1c Inter Measuring CV ≤ 1.5% & Intra Measuring CV ≤ 3% to enable exceptional result management
  • Superior Quality Chromatographic Resolution
Dual Wavelength Detection – To Avoid Interference
  • To Avoid Reagent Peak Interference
  • More Anti-interference Abilities, mutation factor interference to the peak can be easily counteracted
  • To Eliminate the Nonspecific Absorption of Hemoglobin
Degasser – For Better Result Accuracy
  • More Stable Pressure, More Accurate Flow Rate
  • To Reduce Background Absorption and Improve Detection Sensitivity
  • To Improve the Separation Effect of Column and Prolong its Lifetime
Compact Size – To Minimize Space Requirements
  • Small Footprint Reduces Bench Space Needed

Technical Specs

  • Methodology: High - Performance Liquid Chromatography (HPLC)
  • Test Modes: Variant Mode, Thalassaemia Mode
  • Test Range: 3% - 18%
  • Precision: CV ≤ 1.5%
  • Test Speed: 130 Secs / T for Variant Mode, 380 Secs / T for Thalassaemia Mode
  • Sample Type: Venous Blood, Finger Peripheral Blood, Lyophilized Whole Blood, Peripheral Blood, 500µl (150 Dilution Ratio)
  • Auto Sample Station: 10 Positions
  • Photometer: 415nm + 500nm Detector
  • Chromatography Column: Available Test 1600 T for Variant Mode & 800 T for Thalassaemia Mode
  • Filter: 800T
  • Display: 10.1" TFT True Color LCD Touch Screen
  • Software:Linux Software with Self-Diagnosis to Monitor and Detect System Errors
  • Reagent Kit: DX Plus-A, DX Plus-B, DX Plus-C, DX Plus-L, Calibrator, QC Material (Weight Sensor ± 1%)
  • Information Input: Scanner or Touch Keypad
  • Storage: 4000 Sample Results
  • Connection: USB, LAN, LIS Compatible
  • Printer: Thermal Printer and External Laser Printer
  • Operation: Temperature 10 ~ 30°C (50 ~ 86°F)
  • Humidity: ≤ 80%
  • Power: AC 100-240V 50/60HZ 120VA
  • Dimensions: 600mm × 360mm × 540mm (23.6”H × 14.2”W × 21.3”D)
  • Weight: 49KG (108 lbs)
  • Barcode Scanner: QC Curve